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What is Medical DNA Test (PGx)?
iDNA PGx CNS Test is CE marked and certified as an in vitro Diagnostic (IVD) medical device.
It detects variations in specific changes or variations in specific genes that can determine whether a drug could offer an effective treatment for you or if you could develop side effects to specific medication.
What are the Test benefits for me? Do I really need it?
Medical DNA Test (PGx) analysis is a tool that can help your physician determine the appropriate medication treatment for you. That is, with which drug and at what dose you are likely to respond better and experience the least possible side effects. This Test cannot be viewed as a magic wand for your health; however, it can provide your physician with important information about how your body metabolises certain drugs. This information, in conjunction with other factors, such as your age, lifestyle, other medications that you receive and your overall health, will guide your physician in choosing the most suitable treatment for you.
Can you give an example?
Considering the side effects from medication, these may develop because we metabolise drugs differently, depending on our genes. For example, some individuals may metabolise a drug at a slower rate compared with others and, thus, have a higher concentration of this drug in their circulation, which may cause vomiting, headaches, etc. In contrast, other individuals may metabolise a specific drug more rapidly and may experience fewer side effects or require higher doses for effective treatment. This is why physicians today are increasingly recommending the PGx Test for the best possible selection of the appropriate drug for their patients.
How is the Medical DNA Test (PGx) performed?
The Medical DNA Test (PGx) is designed to be an easy and painless test for Central Nervous System (CNS) drugs. All it takes to complete the procedure is a saliva sample. The sample is collected at the physician’s office with a special cotton swab, which is included in a special kit and sent to the certified iDNA Genomics laboratory for analysis. In a few days, you and your physician will receive a complete accurate analysis on the correlations between your genetic variations and specific drugs.
What is the process during which my DNA is analysed and how my own analysis report is extracted?
Saliva contains DNA, which is derived from the oral cavity cells. We send you a complete saliva collection kit and instructions for collecting your sample.
After we have received your saliva sample, our ISO certified laboratory isolates the DNA from your sample. The iDNA Genomics lab then uses state-of-the-art genetic testing procedures to analyse your DNA.
What is the Medical DNA Test (PGx) price?
Medical DNA Test(PGx) retail price is 180 €.
Shipping costs via Geniki Tachydromiki courier are FREE.
Please consult your physician.
Is Medical DNA Test (PGx) safe? How many times do I need to repeat this test?
There is no known danger for collecting saliva sample. The process is simple, fast and non-invasive. Moreover, there is no reason to repeat the test. One time is enough for a particular class of drugs because your genetic profile does not change over time. Ask your physician for more information on Medical DNA Test (PGx) and the drugs it analyses.
What is DNA?
DNA or deoxyribonucleic acid is the cell’s genetic material, packed in units called genes, and contains all the information necessary for all body functions. Genes are the basic unit of heredity and the information they carry determines individuals’ unique characteristics, such as height and eye color. DNA is found in almost all cells of our body (e.g. saliva, skin, etc.).
What is a gene?
Nucleotide sequences in DNA dictate protein synthesis. Proteins are basic functional biological molecules in our body, performing all processes: from signalling and responding to external stimuli to metabolism. The organism’s complete set of genetic material, the complete set of genes, is known as the genome.
What are genetic polymorphisms?
Human DNA is approximately 99.9% identical from person to person. However, there are small differences that make each person unique. These differences are called Single Nucleotide Polymorphisms (SNPs). Some of these variations are associated with certain, unique individual traits or may be linked to a genetic predisposition, which results in differentiated biological function or traits, compared with other individuals. This differentiation may be associated with differentiated needs for exogenous factors (such as nutrition), which need to balance with the differentiated function of the respective gene.
What are alleles?
Alleles are alternative forms of a gene. Each gene is found at a specific genetic locus in DNA and in two forms; as inherited from the parents (one from each biological parent). The forms may be the same (homozygous alleles) or different (heterozygous alleles). The genetic results of the analysis are used to identify each allele or combination of alleles.
What is the association between DNA and medication?
The study of DNA sequencing revealed that several genes directly affect drug metabolism, as well as drug control pathways and, ultimately, the therapeutic benefit that a drug may have for a particular patient. It is due to our genes that the same drug at the same dose can affect patients with the same disease in very different ways. Genes can also be the reason why some people have serious side effects after taking a drug, while others have none.
No person and no disease is the same. Each patient may respond differently to medication.
Are the PGx analysis results comprehensible?
The analysis results are in Greek and English. They are detailed and fully comprehensible by the specialised physician. The physician’s expertise and experience is necessary for the correct result interpretation to the patient.
ATTENTION: Do not change the dose or the timimg of the medication you are taking, without the advice of your physician.
What is Pharmacogenetics (PGx)
Pharmacogenetics combines pharmacology with genetics (studies how drugs act in the body).
What are Nutrition & Exercise DNA Tests?
Nutrition & Exercise DNA Tests study how our genes affect nutrient metabolism from the food we eat, the elimination rate of toxins, our predisposition to weight gain, as well as our body's response to various types of exercise and many other activities.
What are Nutrition, Sports & Exercise Genomics?
Nutritional Genomics (Nutrigenetics & Nutrigenomics) examine the interactions between genes and nutrition in relation to health. Personalised / Precision Nutrition (PN) is defined as the set of specially designed nutrition tips based on an individual’s genotype, phenotype and lifestyle information and aim at improving eating behaviour for better health.
Sport and Exercise Genomics focus on understanding the genome in relation to athletic performance. An individual's athletic ability is determined by two key factors: his genome and the environment, making athletic performance a complex phenotype. Genetic polymorphisms affect metabolic processes in the human body, such as performance, endurance, muscle fiber components, neuromuscular coordination and oxygen uptake.
What is the benefit of this test for me?
We are all different and this is why there is no diet and exercise plan that suits everyone, i.e. ‘no size fits all’. The genetic information included in your personal genetic analysis will provide you with a deeper understanding of your needs, thus you can choose the appropriate diet plan exercise programme for you.
Keep in mind that genetics is one of many factors that contribute to our health and well-being. Therefore, for the best results, please use your genetic profile as part of the overall picture and not individually.
How often do I need to take the DNA test?
Our DNA does not change. You can take the iDNA Genomics test once in a lifetime, without the need for repetition. You will therefore be able to make your own personalised plan, based on your own, unique genetic profile.
What is the process during which my DNA is analysed and how my own analysis report is extracted?
Saliva contains DNA, which is derived from the oral cavity cells. We send you a complete saliva collection kit and instructions for collecting your sample.
After we have received your saliva sample, our ISO certified laboratory isolates the DNA from your sample. The iDNA Genomics lab then uses state-of-the-art genetic testing procedures to analyse your DNA.
What is the amount of saliva that needs to be sent?
It is crucial to follow the procedure described in the PROCESS section to ensure that the sample size is sufficient to isolate DNA. In the test kit, you will find 2 sterile saliva swabs, each further packaged in a special collection tube. You need to follow the saliva collection procedure exactly as described in the instructions. It is very important to collect the sample with approximately 20 intense rotational movements, up and down, on each cheek. for at least 1 minute in total.
What is the information I will receive through my personal analysis report?
In the PRODUCTS section, you can find in detail all the pilars and categories of analysis provided by the results report in each test. The genetic test provides the analysis of our genetic profile on aspects such as predispositions and nutrient needs, so that our diet and sports choices can become personalised.
Learn more here
How will I receive my personal analysis report?
Within 15 business days of receiving your sample at iDNA Genomics laboratory, your genetic analysis report will be sent to the email address you have provided in the filled-in forms.
What does my personal analysis report have to do with my current health status?
Your personal genetic analysis shows your genetic predisposition in relation to weight management, nutrient metabolism, heart health, food sensitivities, injury predisposition, as well as predisposition for high performance in specific sports. If your genetic test shows, for example, that you have a ‘High Sensitivity’ profile for a specific vitamin metabolism, this does not necessarily mean that a blood test will show a deficiency in this vitamin. After all, vitamin levels depend on many factors, such as the intake of this vitamin through the diet and the interaction with other nutrients. This knowledge shows the body's predisposition to deficiency and has an advisory role in choosing the appropriate diet for optimal health.
Can I interpret my own genetic analysis results, or do I need expert consultation?
It is important to note that genetics is one of many factors that contribute to our health and well-being. Therefore, for the best results, it is recommended you use your genetic profile as part of the overall picture and not individually. Please read your analysis carefully. To make the most of the information provided, discuss the results with your nutritionist, your trainer or your physician, who are able to help you make individualised recommendations based on your personal genotype, phenotype, medical history and lifestyle.
What is the basis of the genetic analysis results?
The report of the results of each personal genetic analysis is based on the latest documented scientific research that has been published in scientific journals, through the process of peer-review and have been evaluated by the scientific team of iDNA Genomics. Each report is based on published research investigating the effects of nutrition, exercise and many other factors that affect health and well-being.
What is DNA?
DNA or deoxyribonucleic acid is the cell’s genetic material, packed in units called genes, and contains all the information necessary for all body functions. Genes are the basic unit of heredity and the information they carry determines individuals’ unique characteristics, such as height and eye color. DNA is found in almost all cells of our body (e.g. saliva, skin, etc.).
What is a gene?
Nucleotide sequences in DNA dictate protein synthesis. Proteins are basic functional biological molecules in our body, performing all processes: from signalling and responding to external stimuli to metabolism. The organism’s complete set of genetic material, the complete set of genes, is known as the genome.
What are genetic polymorphisms?
Human DNA is approximately 99.9% identical from person to person. However, there are small differences that make each person unique. These differences are called Single Nucleotide Polymorphisms (SNPs). Some of these variations are associated with certain, unique individual traits or may be linked to a genetic predisposition, which results in differentiated biological function or traits, compared with other individuals. This differentiation may be associated with differentiated needs for exogenous factors (such as nutrition), which need to balance with the differentiated function of the respective gene.
What are alleles?
Alleles are alternative forms of a gene. Each gene is found at a specific genetic locus in DNA and in two forms; as inherited from the parents (one from each biological parent). The forms may be the same (homozygous alleles) or different (heterozygous alleles). The genetic results of the analysis are used to identify each allele or combination of alleles.
What is genotype?
In a broad sense, the term genotype refers to the genetic makeup of an organism. In other words, it describes the complete set of genes of an organism. The term can be used to refer to alleles, that is, variants of a gene carried by an organism.
What is phenotype?
The phenotype describes all the observable characteristics of an organism that result from the interaction of their genotype (total genetic inheritance) with the environment. The phenotype can change constantly throughout an individual’s life due to environmental changes, as well as physiological and morphological changes associated with ageing. Different environments can affect the evolution of inherited traits and alter the expression of similar genotypes (for example, twins maturing in different families).