Science - iDNA Genomics

Nutrition, Sports & Exercise Genomics

Nutrition Genomics

Nutritional Genomics (Nutritigenetics & Nutritigenomics) examine the interactions between genes and nutrition in relation to health.

Personalised / Precision Nutrition (PN) is defined as the set of especially designed nutrition tips based on an individual’s genetic, phenotypic and lifestyle information aimed at improving eating behaviour towards better health.

The iDNA Test aids in effective weight loss and management, the prevention of potential vitamin and mineral deficiencies, the reduction of risk for chronic diseases related to nutrition, as well as in identifying possible food sensitivities.

Sports & Exercise Genomics

Sports & Exercise Genomics focuses on understanding the genome in relation to athletic performance.

An individual's athletic ability is determined by two key factors: his genome and the environment, making athletic performance a complex phenotype. Genetic polymorphisms affect metabolic processes in the human body, such as performance, endurance, muscle fiber components, neuromuscular coordination and oxygen uptake.

Therefore, a genetic test is a useful tool for talent identification in sports, choosing the right sport and injury predisposition. This knowledge will be translated into a personalised training programme for maximum performance and injury prevention.

Facts...

Weight management

Individuals who followed a diet based on their DNA decreased their total fat intake by 6%, improved their overall diet quality by 15% and maintained these changes for longer, compared with individuals who received general diet recomendations.

Source:(de Luis et al., 2015)

Cardiovascular health

Individuals who carry the T allele of the rs7903146 polymorphism have double the risk for developing metabolic syndrome (central obesity, insulin resistance, hypertension) when consuming up to the recommended amounts of saturated fats (10% of daily energy intake) in their diet.

Source: (Bodhini et al., 2017)

Vitamin absorption

Carriers of the T allele of the rs1801133 polymorphism experience an up to 60% reduction in folate metabolism and 20% lower serum folate compared with non-carriers.

Source: (Vidmar Golja et al., 2020)

Athletic profile

Individuals carrying the G allele of the rs4253778 polymorphism have 65% higher likelihood for elite performance in endurance sports.

Source: (Petr et al., 2019)

Food sensitivity

C carriers of the rs762551 polymorphism are characterised by slower caffeine metabolism compared with non-carriers of the C allele, which leads to symptoms of insomnia and stress.

Source: (Fulton et al., 2018)

Detoxification capacity & antioxidant needs

Carriers of the T allele of the polymorphism rs4880 are characterised by lower capacity to remove the harmful free radicals from their body compared with non-carriers. Sufficient antioxidant intake such as beta-carotene, lycopene and alpha-tocopherol reduce free radical accumulation in the body by 30%.

Source: (Paludo et al., 2013)

Mineral metabolism

G carriers of the rs4820268 polymorphism exhibit an elevated risk for iron deficiency and iron deficiency anaemia by 1.5 fold and 2 fold, respectively. These individuals are advised to emphasise on heme-iron dietary sources (animal foods).

Επιστημονικό άρθρο: (Gichohi-Wainaina et al., 2014)

Injury predisposition

Individuals carrying the Τ allele of the rs12722 polymorphism of COL5A1 gene have a higher predisposition for Achilles tendon, knee and elbow injuries by 1.5 fold.

Source: (Vaughn, Stepanyan, Gallo and Dhawan, 2017)

*Selection of the appropriate polymorphisms and the interpretation of our individual genetic profile is based on the latest scientific data. Above are some of the most representative surveys on each pilar of analysis.

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