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We are here
to support you for
your patients’ benefit
Genetic predisposition to cardiovascular diseases –
Polygenic Risk Score
(PRS)
Pharmacogenetics of Central Nervous system drugs
PRS is associated with the prospect of intervention, including prioritization of preventive measures and presymptomatic testing, initiation and frequency of testing, as well as lifestyle modification and clinical decision-making.
Benefits of Cardio Health for healthcare professionals
Improving cardiovascular disease risk underestimation
Current tools for assessing the occurrence of cardiovascular diseases may significantly underestimate the risk.
The PRS can be used by the physician to reclassify individuals whose risk had been underestimated, for example from an intermediate risk category to a high-risk category.
Scientific article: Ripatti, S., et al., 2010
Tikkanen, E., et al., 2013
Improving compliance and efficiency
Individuals who have knowledge of their PRS, and specifically those at higher risk, demonstrate higher compliance with their treatment or favorable lifestyle changes.
The higher the treatment adherence, the greater its effectiveness. On the contrary, poor adherence can lead to treatment failure.
Scientific article:Kullo, I.J., et al., 2016
Umans-Eckenhausen, M.A., et al., 2003
Higher benefits of primary prevention in high-risk individuals
The higher the treatment adherence, the greater its effectiveness. On the contrary, poor adherence can lead to treatment failure.
People with a high PRS (>80% of the population) are at a particularly increased risk of undesired disease manifestation. By initiating primary prevention (e.g. statin therapy), high-risk individuals benefit more by achieving a significantly greater reduction in their relative ten-year risk.
Scientific article:Mega, J.L., et al., 2015
Natarajan, P., et al., 2017
Prevalence of coronary artery disease and atrial fibrillation by PRS percentile.
Coronary artery calcification by lifestyle and PRS.
Coronary heart disease events by statin treatment and PRS category.
Στο iDNA Cardio Health εξετάζεται πληθώρα γονιδίων που συμβάλουν στην εκτίμηση του ρίσκου εμφάνισης καρδιαγγειακών παθήσεων. Δείτε εδώ αναλυτική λίστα των γονιδίων.
Genes examined
The iDNA Cardio Health examines a plethora of genes that contribute to the risk of developing cardiovascular diseases.
iDNA Cardio
Health Kit
The iDNA Cardio Health kit is an in vitro diagnostic (IVD) medical device of Genetic Analysis and phenotypic traits for the early prevention of cardiovascular disease based on the Polygenic Risk score (PRS & Adjusted PRS).
The iDNA Cardio Health kit is an in vitro diagnostic (IVD) medical device bearing the CE mark and has been notified to the National Medicines Agency (EOF) Medical Devices Register "Gremdis" (Protocol No. 54882 / 23-05-2022).